Hastelloy C-22 is a versatile nickel-chromium-molybdenum alloy with better overall corrosion resistance than other Ni-Cr-Mo alloys available today, including hastelloy C-276, C-4, and A625.Hastelloy C-22 has outstanding resistance to pitting, crevice corrosion and stress-corrosion cracking. It has excellent resistance to oxidizing aqueous media including acids with oxidizing agents, wet chlorine and mixtures containing nitric acid or oxidizing acids with chlorine ions. Hastelloy C-22 has outstanding resistance to both reducing and oxidizing media, and because of its versatility can be used where "upset" conditions are likely to occur or in multipurpose plants.

Hastelloy C-22 has exceptional resistance to a wide variety of chemical process environments, including strong oxidizers such as ferric and cupric chlorides, hot contaminated media (organic and inorganic), chlorine, formic and acetic acids, acetic anhydride, and seawater amd brine solutions.Hastelloy C-22 resists the formation of grain boundary precipitates in the weld heat affected zone, thus making it suitable for most chemical process applications in the as-welded condition.

Hastelloy C-22 can be fabricated using the same techniques as are used for alloys C-276 or C-4. It can be welded, forged, hot-upset and impact extruded. Alloy C-22 can also be successfully deep-drawn, spun, press formed or punched, although the alloy tends to work-harden.Parts which have been hot formed or severely cold formed should be heat treated at 2050  and rapid quenched prior to final fabrication or installation.

Hastelloy C-22 is covered by ASME . Plate, sheet, strip, bar, tubing, and pipe are covered by ASME specifications SB-574, SB-575, SB-619, SB-622 and SB-626 and by ASTM specifications B-574, B-575, B-619, B-622 and B-626. The UNS number is NO6022.

Some of the area of present or potential use for alloy C-22 are: Acetic acid/Acetic Anhydride, cellophane manufacturing, chlorine spargers, chlorination systems, circuit board etching equipment, complex acid/chemical mixtures, fans and blowers, galvanizing line equipment, gas scrubber systems, geothermal wells, HF furnaces, incineration systems, nuclear fuel reprocessing, pesticide production, phosphoric acid applications, pickling system components, plate heat exchangers, selective leaching systems, sulfur oxide cooling towers, sulfonation systems, and tubular heat exchangers.